mindmap root((疏远)) estrange implies the development of indifference or hostility with consequent loss of sympathy or divorcement: had become ~d from their family after years of neglect. alienate may or may not suggest separation but always implies loss of affection or interest: managed to ~ all her coworkers with her arrogance. disaffect refer to those from whom loyalty is expected or demanded and stresses the effects, such as rebellion or discontent, of alienation without actual separation: a coup led by ~ed party members. wean implies a commendable separation from something on which one is weakly or immaturely dependent: ~ yourself from a bad habit.